Admira 80 mg

Description

Indications
Admira is an oral antidiabetic medication belonging to the sulfonylurea group. It is prescribed to manage type 2 diabetes mellitus in adults, especially when blood sugar control is inadequate with diet, exercise, and weight loss alone. It helps lower blood sugar levels by supporting the body’s natural insulin production.

Always use this medication as advised by a registered healthcare professional.

Pharmacology
Admira contains Gliclazide, a second-generation sulfonylurea. Gliclazide stimulates insulin release from the pancreas by enhancing calcium (Ca+2) transport across pancreatic beta-cell membranes, and it also reduces glucose production in the liver. These actions help to improve blood sugar control in individuals with type 2 diabetes.

Dosage & Administration

• Film-coated Tablet:
  The usual starting dose is 40 to 80 mg per day. Depending on your response to treatment, the dose may be increased to a maximum of 320 mg per day, taken in divided doses. It should be taken before meals.

• Modified Release (MR) Tablet:
  Your doctor will adjust the dose according to your blood and possibly urine sugar levels. The recommended daily dose is between one to four tablets (maximum 120 mg), taken once daily at breakfast. It is important to take your tablet(s) with a glass of water at breakfast and to avoid chewing or crushing the tablets. You must consume a meal after taking the tablets.

• Combination Therapy:
  If you’re prescribed a combination of Admira with other antidiabetic drugs, such as metformin, GLP-1 receptor agonists, or insulin, your doctor will determine the appropriate doses for each medicine.

Overdose and Missed Dose

• Overdose:
  If you take more Admira than prescribed, contact your doctor or the nearest hospital immediately. Overdose symptoms may include hypoglycemia (low blood sugar). You can counteract mild hypoglycemia by consuming sugar or sugary drinks, followed by a substantial meal. If the patient is unconscious, seek emergency medical help.

• Missed Dose:
  If you miss a dose, take it as soon as you remember. If the next dose is nearly due, skip the missed dose. Do not take a double dose to compensate.

Important Notes

• Stopping Admira without medical consultation could lead to hyperglycemia (high blood sugar), increasing the risk of diabetes-related complications. Always consult your doctor before discontinuing treatment. Follow your healthcare provider’s instructions regarding medication use.

Drug Interactions
Admira may interact with several other medications, affecting blood sugar levels. It can enhance the hypoglycemic effects when taken with other antidiabetic drugs (oral agents, GLP-1 receptor agonists, insulin), certain antibiotics, heart and blood pressure medications (e.g., beta-blockers), antifungal treatments, and some painkillers (e.g., ibuprofen).
On the other hand, the blood-sugar-lowering effect of Admira may be weakened by drugs like corticosteroids, certain antidepressants (e.g., monoamine oxidase inhibitors), and asthma treatments.

Always inform your doctor if you are using any other medications, especially when hospitalized.

Admira with Food and Drink
Admira can be taken with food and non-alcoholic drinks. However, alcohol consumption should be avoided, as it can unpredictably affect blood sugar control.

Precautions & Warnings

• Hypoglycemia (Low Blood Sugar):
  Risk factors include skipping meals, fasting, excessive physical activity, alcohol consumption, or taking higher doses than prescribed. Symptoms of hypoglycemia may include headache, dizziness, sweating, irritability, and confusion. Always carry a source of sugar (e.g., glucose tablets) to treat hypoglycemia.

• Hyperglycemia (High Blood Sugar):
  If your blood sugar is not adequately controlled, symptoms like thirst, frequent urination, and fatigue may occur. Follow your doctor’s treatment plan strictly to avoid these issues.

• Liver or Kidney Problems:
  Gliclazide should be used with caution in patients with liver or kidney issues. Regular monitoring of liver and kidney function is essential during treatment.

Contraindications
Do not use Admira if you:

• Are allergic to gliclazide or any other sulfonylurea medications.
• Have type 1 diabetes or diabetic ketoacidosis.
• Have severe liver or kidney disease.
• Are pregnant or breastfeeding.

Side Effects
Common side effects of Admira include:

• Hypoglycemia: The most frequent side effect, which can cause drowsiness, confusion, or loss of consciousness if untreated.
• Liver Disorders: Rare cases of liver dysfunction may cause jaundice (yellowing of the skin or eyes).
• Skin Reactions: Rashes, itching, or hives may occur. In severe cases, stop using the medication and seek immediate medical advice.
• Blood Disorders: Decreased blood cell counts may lead to symptoms like pale skin, prolonged bleeding, or fever.
• Digestive Issues: Abdominal pain, nausea, and diarrhea are possible, especially when not taken with food.
• Eye Disorders: Changes in vision may occur, particularly at the start of treatment, due to blood sugar fluctuations.

Pregnancy & Lactation
Admira is not recommended for use during pregnancy. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medication.

Storage Conditions
Store Admira in a cool, dry place below 30°C, away from light and moisture. Keep it out of reach of children. Do not use the medication after the expiry date. Dispose of unused medicine properly to protect the environment.

Chemical Structure

• Molecular Formula: C15H21N3O3S

Common Questions about Admira 80 mg Tablet

• What is Admira 80 mg Tablet?
  It is an oral medication used to control blood sugar levels in type 2 diabetes by stimulating insulin release and improving insulin sensitivity.

• What happens if I take Admira 80 mg Tablet without eating?
  Take Admira 80 mg with food. If you skip a meal, skip the dose.

• What if I miss a dose?
  Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule.

• How long does the effect last?
  The effect of Admira typically lasts for up to 24 hours.

• Are there pregnancy warnings?
  Admira is not recommended for pregnant women.

General Instructions

• Take Admira 80 mg as directed by your doctor, typically 30 minutes before breakfast.
• Regularly monitor your blood sugar levels.
• Carry a source of sugar with you at all times in case of hypoglycemia.
  Always follow your doctor’s instructions and guidelines.