Alzolam 0.5 mg

Description

Indications
Alzolam is prescribed for the following conditions:

• Anxiety disorders
• Short-term relief of anxiety symptoms
• Anxiety associated with depression
• Panic disorder, with or without agoraphobia
  Use this medication only as directed by a registered physician.

Pharmacology
Alprazolam belongs to the 1,4-benzodiazepine class and is a triazole derivative. It acts as an anxiolytic with hypnotic and anticonvulsant properties. Alprazolam is believed to exert its effects by interacting with the Gamma-Aminobutyric Acid (GABA)-benzodiazepine receptor complex. Like other benzodiazepines, its effects on the central nervous system (CNS) range from mild impairment of task performance to sedation, depending on the dose administered.

Dosage & Administration
The initial recommended dosage is 0.25 mg to 0.5 mg taken three times daily. Based on patient response, the dosage may be increased at intervals of 3 to 4 days in increments not exceeding 1 mg per day. The maximum daily dose should not exceed 4 mg. In some cases, patients with panic disorder may require doses up to 10 mg per day, necessitating periodic reassessment and potential dosage adjustments.

Dosages should be tailored for optimal therapeutic benefit while minimizing adverse effects. If side effects occur at the starting dose, the dosage should be lowered. When discontinuing the medication, the dose should be tapered gradually, reducing by no more than 0.5 mg every three days.

For elderly patients or individuals with advanced liver disease, the starting dose is typically 0.25 mg, taken two or three times daily. Dosage increases should be gradual and only if well tolerated.

For patients transitioning from multiple daily doses of Alprazolam 0.25 mg or 0.5 mg, a single daily dose of Alprazolam 1 mg is recommended, preferably in the morning. The tablets must be swallowed whole and should not be chewed, crushed, or broken.
Use this medication only as directed by a registered physician.

Drug Interactions
The CNS-depressant effects of Alzolam may be enhanced when taken with other psychotropic drugs, anticonvulsants, antihistamines, alcohol, or oral contraceptives.

Side Effects
Side effects, if experienced, are most common at the beginning of treatment and typically subside with continued use. The most frequently reported side effects include:

• Drowsiness
• Light-headedness
• Depression
• Headache
• Confusion
• Dry mouth
• Constipation

Pregnancy & Lactation
Alprazolam is classified under pregnancy category D, indicating that it should be avoided during pregnancy. As with other benzodiazepines, Alprazolam is likely excreted in breast milk; therefore, breastfeeding is not recommended for mothers using this medication.

Precautions & Warnings
Alzolam has the potential to cause psychological and physical dependence. Dosage adjustments or abrupt discontinuation should only be done under medical supervision. The duration of treatment should be determined by a physician. Caution is advised when administering Alzolam to patients with hepatic or renal impairment, chronic pulmonary insufficiency, or sleep apnea.

Use in Special Populations
The safety and effectiveness of Alzolam in individuals below 18 years of age have not been established.

Overdose Effects
Symptoms of Alzolam overdose may include drowsiness, confusion, impaired coordination, reduced reflexes, and in severe cases, coma. Treatment should focus on supportive measures, including immediate gastric lavage.

Therapeutic Class
Benzodiazepine sedatives

Storage Conditions
Store below 30°C in a dry place, away from direct light and moisture. Keep out of the reach of children.