Antista 2 mg/5 ml

Description

Indications

Antista is indicated for the following conditions:

• Urticaria (hives)
• Sensitivity reactions
• Angioneurotic edema (swelling beneath the skin)
• Vasomotor rhinitis (allergic rhinitis)
• Cough
• Common cold
• Motion sickness
• Other allergic conditions

Use as directed by a registered physician.

Pharmacology

Antista contains Chlorpheniramine Maleate, an alkylamine antihistamine, which is one of the most potent H1-receptor blocking agents. Chlorpheniramine Maleate is widely used as an effective antihistamine with less sedation compared to other antihistamines such as promethazine. It works by competitively blocking H1-receptors to reduce allergic reactions.

Dosage & Administration

• Adults: The usual adult dose is 4 mg every 4-6 hours, with a maximum of 24 mg daily.
• Children:
  • 6-12 years: 2 mg every 4-6 hours, with a maximum of 12 mg daily.
  • 2-5 years: 1 mg every 4-6 hours, with a maximum of 6 mg daily.
  • 1-2 years: 1 mg twice daily.
  • Below 1 year: The use of Chlorpheniramine Maleate is not recommended.

Use as directed by a registered physician.

Interaction

Chlorpheniramine Maleate may be incompatible with:

• Calcium chloride
• Kanamycin sulfate
• Noradrenaline acid tartrate
• Pentobarbital sodium
• Meglumine adipiodone

Contraindications

Antista is contraindicated in:

• Patients who are hypersensitive to Chlorpheniramine Maleate.
• Newborns or premature infants.

Side Effects

Antista is generally well-tolerated, but some side effects may include:

• Drowsiness
• Dizziness
• Muscular weakness
• Gastrointestinal upset

Pregnancy & Lactation

This medication should not be used during pregnancy, especially during the first trimester, or by lactating mothers.

Precautions & Warnings

• Use with caution in patients with glaucoma or prostatic hypertrophy.
• Caution should be exercised while driving or operating machinery during treatment with Chlorpheniramine.

Overdose Effects

Symptoms of overdose may include:

• CNS depression (sedation, apnea, cardiovascular collapse)
• CNS stimulation (insomnia, hallucinations, tremors, convulsions)
• Tinnitus (ringing in the ears), blurred vision, dizziness, ataxia (lack of coordination), hypotension (low blood pressure)
• Anticholinergic effects (dry mouth, fixed dilated pupils, flushing, hyperthermia, gastrointestinal symptoms) are more likely in children.

Therapeutic Class

Sedating Anti-histamine

Storage Conditions

Store in a cool, dry place below 25°C, protected from light. Keep out of the reach of children.