Calbo Jr 250 mg

Indications

250 mg or 500 mg tablet:
Calbo Jr is indicated for the treatment and prevention of calcium deficiency in patients with insufficient dietary intake. Conditions commonly associated with calcium depletion include hypoparathyroidism, achlorhydria, chronic diarrhea, vitamin D deficiency, steatorrhea, sprue, pregnancy, lactation, menopause, pancreatitis, renal failure, alkalosis, and hyperphosphatemia. Calcium Carbonate is frequently utilized to treat hyperphosphatemia, particularly in chronic renal failure patients and those undergoing continuous ambulatory peritoneal dialysis (CAPD) or hemodialysis. Many individuals are unable to tolerate large doses of calcium carbonate for effective phosphate control and may require additional approaches, such as dietary phosphate restriction or the use of small doses of aluminum hydroxide. Although Calcium Carbonate-based preparations can offer short-term relief from dyspeptic symptoms, they are no longer recommended for long-term use in peptic ulcer treatment.

1000 mg tablet:
Calbo Jr is also indicated for managing conditions linked to acidity, such as acid indigestion, heartburn, sour stomach, and general upset stomach. It provides fast relief of hyperacidity-related discomfort.

Follow the advice of a registered healthcare professional regarding dosage.

Pharmacology

Calcium Carbonate works by reacting with gastric acid to form a salt and water. The reaction is as follows:
CaCO3 + 2HCl → CaCl2 + H2O + CO2.
When 2 grams of Calcium Carbonate are ingested, it effectively raises the pH of 100 ml of hydrochloric acid above 6. This increase in pH diminishes pepsin activity in the stomach. Up to 30% of the ingested calcium may be absorbed by the body.

Dosage & Administration

250 mg or 500 mg tablet:
For adults, the recommended dosage of Calcium Carbonate, when used as an antacid, ranges between 540 mg to 2000 mg per day, depending on individual needs. Children should receive half the adult dosage. As a dietary supplement, such as for the prevention of osteoporosis, the recommended dose is 1250-3750 mg of Calcium Carbonate daily (equivalent to 500-1500 mg of calcium). Dosing may vary depending on conditions such as calcium deficiency, malabsorption, or parathyroid function. For pregnant or lactating women, the daily calcium intake should be between 1200-1500 mg. In patients with chronic renal failure, the dose may range from 2.5-9.0 grams of Calcium Carbonate daily, adjusted based on individual needs. To enhance phosphate binding, Calcium Carbonate should be taken with meals.

1000 mg tablet:
Take 2000-3000 mg as symptoms occur, and repeat the dose hourly if necessary or as directed by a healthcare provider.

Follow the advice of a registered healthcare professional regarding dosage.

Interaction

Calcium Carbonate may enhance the effects of digoxin and other cardiac glycosides, especially if hypercalcemia occurs. It may also interfere with the absorption of certain medications, such as tetracyclines (e.g., doxycycline, minocycline, oxytetracycline) and other calcium supplements. In patients with chronic renal failure, modifying vitamin D therapy may be required to avoid hypercalcemia when using Calcium Carbonate as the primary phosphate binder.

Contraindications

• Hypercalcemia
• Hyperparathyroidism
• Hypercalciuria and nephrolithiasis
• Zollinger-Ellison syndrome
• Concurrent use with digoxin (requires careful monitoring of serum calcium levels)

If hypercalcemia occurs, discontinuation of Calcium Carbonate typically restores normal calcium levels. Calcium salts should be used with caution in patients with conditions like sarcoidosis, renal disease, heart disease, or those receiving cardiac glycosides.

Side Effects

Common side effects of oral Calcium Carbonate include gastrointestinal irritation and constipation. Although hypercalcemia is rare when calcium is taken alone, it can occur when high doses are administered, particularly in patients with chronic renal failure. If any discomfort like nausea, vomiting, stomach cramps, dry mouth, increased thirst, or urination is experienced, consult a healthcare provider.

Pregnancy & Lactation

Calcium Carbonate has been widely used during pregnancy for oral supplementation and as an antacid. It is also considered safe for use during breastfeeding. However, it should only be used according to the recommendations of a healthcare professional.

Use in Special Populations

Use in Children:
Calcium Carbonate has been extensively studied and found safe and effective for use in children, especially those with chronic renal failure.

Use in Elderly:
In elderly patients with renal failure, constipation may become troublesome due to Calcium Carbonate. Regular monitoring of serum calcium and phosphate levels is essential for elderly patients to avoid complications.

Therapeutic Class

Specific mineral preparations, essential for bone formation and calcium supplementation.

Storage Conditions

Store in a cool, dry place, away from light and heat. Keep out of reach of children