Calboral-D 500 mg+200 IU

Description

Here’s the rewritten and well-structured product description for Calboral-D Tablet:

Indications

Calboral-D Tablet is recommended for the prevention and treatment of various conditions, including:

• Osteoporosis (a condition where bones become weak and brittle)
• Osteomalacia (softening of the bones due to vitamin D deficiency)
• Tetany (muscle spasms caused by calcium deficiency)
• Hypoparathyroidism (a condition where the parathyroid glands produce insufficient hormone)
• Disorders of osteogenesis (conditions affecting bone formation)

This supplement is also beneficial for individuals who do not get adequate calcium in their diet, including:

• Children with insufficient calcium intake
• Rickets
• Pregnancy and lactation
• Elderly patients Additionally, Calboral-D can be used as a supplement for individuals suffering from pancreatitis and as a phosphate binder in cases of chronic renal failure.

Note: Always consult a registered healthcare professional before using this medicine.

Composition

Each Calboral-D Tablet contains the following active ingredients:

• Calcium Carbonate USP 1250 mg (sourced from coral), which is equivalent to 500 mg of elemental Calcium.
• Vitamin D USP 200 IU (helps in calcium absorption and bone health).

Alternatively, the DX tablet contains:

• Calcium Carbonate USP 1500 mg (sourced from coral), which is equivalent to 600 mg of elemental Calcium.
• Vitamin D USP 400 IU.

The effervescent tablet contains:

• Calcium Carbonate USP 1500 mg (coral source), which is equivalent to 600 mg of elemental Calcium.
• Vitamin D3 (Cholecalciferol USP) 400 IU.

Pharmacology

Calcium plays a crucial role in various bodily functions, and its deficiency can lead to severe health issues. Clinical studies indicate that Calcium supplementation is beneficial for the prevention and management of osteoporosis and related fractures. Vitamin D is essential for enhancing the absorption of calcium from the gastrointestinal tract and promoting bone formation.

In this formulation, Calcium Carbonate is derived from coral, which has a chemical structure resembling that of human bones. This similarity supports better absorption compared to other calcium sources. Vitamin D3 assists in the efficient absorption of calcium and helps maintain calcium balance in the body, making it an ideal combination for bone health.

Dosage & Administration

The recommended dosage is:

• One tablet daily, or as prescribed by your physician.
• Take with plenty of water and preferably after a meal for optimal absorption.
• For effervescent tablets, dissolve one tablet in a glass of water, stir the solution, and drink it orally.

Note: Follow your doctor’s guidance for proper dosage.

Interactions

Certain medications can interact with Calboral-D:

• Thiazide diuretics may reduce calcium excretion in urine, increasing the risk of hypercalcemia. Regular calcium monitoring is advised.
• Corticosteroids can reduce calcium absorption, so calcium dosage adjustments may be needed.
• Ion exchange resins (e.g., cholestyramine) and laxatives (e.g., paraffin oil) may interfere with Vitamin D absorption.
• Tetracycline antibiotics should be taken at least 2 hours before or 4-6 hours after Calboral-D to avoid absorption interference.
• Bisphosphonates or sodium fluoride should be taken at least 3 hours after Calboral-D to ensure effective absorption.

Foods high in oxalic acid (like spinach) or phytic acid (found in whole grains) may reduce calcium absorption.

Contraindications

Do not use Calboral-D if you have any of the following conditions:

• Hypercalcemia (high calcium levels)
• Hyperparathyroidism (overactive parathyroid glands)
• Hypercalciuria (excessive calcium in urine) or kidney stones
• Severe renal insufficiency
• Allergic reactions to any components of the product
• Concomitant use with digoxin (requires careful monitoring of calcium levels)

Side Effects

Common side effects may include:

• Constipation
• Nausea and vomiting
• Dry mouth
• Drowsiness
• Headache

More serious side effects may occur if taken in excess, such as hypercalcemia (high calcium levels), which can cause symptoms like muscle weakness, fatigue, bone pain, and in extreme cases, heart arrhythmias or coma.

Pregnancy & Lactation

Calboral-D is generally safe for use during pregnancy and breastfeeding, but it should not exceed 1500 mg of calcium and 600 IU of Vitamin D per day. Overdoses of calcium or vitamin D during pregnancy may lead to adverse effects on the fetus. Consult your doctor before using this product during pregnancy or lactation.

Precautions & Warnings

• Monitor serum calcium levels and renal function during long-term treatment.
• Use caution in patients with renal insufficiency or sarcoidosis (a condition that may increase vitamin D metabolism).
• In elderly patients or those on cardiac medications, frequent monitoring of calcium levels is recommended.
• Take with caution in immobilized patients or those with osteoporosis to avoid the risk of hypercalcemia.

Overdose Effects

Excessive intake may lead to hypercalcemia, with symptoms like nausea, vomiting, constipation, and confusion. Severe overdose may result in kidney damage, soft tissue calcification, and life-threatening complications such as cardiac arrhythmias or coma. Treatment involves discontinuing the medication, rehydration, and monitoring of electrolytes and renal function.

Therapeutic Class
This medication falls under the category of Specific mineral & vitamin combined preparations.

Storage Conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.

Common Questions about Calboral-D 500 mg Tablet

1. What is Calboral-D 500 mg Tablet?
   • A combination of calcium carbonate and vitamin D3, designed to prevent and treat calcium and vitamin D deficiency.
2. What are the benefits of Calboral-D 500 mg Tablet?
   • It helps prevent osteoporosis, treats rickets, and improves bone health, especially in elderly individuals.
3. Who should avoid Calboral-D 500 mg Tablet?
   • Those with high calcium levels, kidney stones, sarcoidosis, or allergies to any ingredient in the tablet.
4. What are the side effects?
   • Common effects include constipation, nausea, and dry mouth. Serious effects like hypercalcemia can occur if taken in excess.
5. How should I take Calboral-D?
   • Typically one tablet per day with food, or as advised by your doctor.
6. What precautions should I take?
   • Be cautious if you are pregnant, breastfeeding, or have kidney issues. Monitor calcium levels when using this product long-term.