Cinaron Plus 20 mg+40 mg

Description

Indications

Cerebral Circulatory Disorders:
Cinarzin Plus is indicated for the prevention and long-term management of symptoms associated with cerebral vascular conditions such as cerebral spasms and arteriosclerosis. It is effective in alleviating symptoms like dizziness, tinnitus (ear ringing), vascular headaches, irritability, fatigue, and disruptions in sleep cycles, including premature awakening. Additionally, it is beneficial for treating age-related conditions such as involutional depression, memory loss, difficulty concentrating, and incontinence.

Sequelae of Cerebral and Cranial Trauma:
It is also used to manage symptoms following brain and head injuries.

Post-Apoplexy Disorders:
Cinarzin Plus aids in the recovery and management of symptoms following a stroke (apoplexy).

Migraine Relief:
This medication provides relief from migraine symptoms and can be used for migraine prophylaxis.

Peripheral Circulatory Disorders:
For individuals suffering from peripheral circulatory issues, Cinarzin Plus offers prophylactic and maintenance treatment for symptoms of vascular spasms and arteriosclerosis. This includes conditions such as obliterating arteritis, thromboangitis obliterans, Raynaud’s disease, and complications related to diabetes, including acrocyanosis, and pernio. It is also used to treat symptoms like intermittent claudication, trophic disturbances, pre-gangrene, and trophic or varicose ulcers. Other issues like paraesthesia, cold extremities, and nocturnal cramps are also managed effectively.

Disorders of Balance:
Cinarzin Plus is particularly effective for individuals suffering from balance disorders caused by labyrinthine arteriosclerosis and vestibular disturbances. It is also useful in treating Meniere’s syndrome, offering relief from vertigo, dizziness, nausea, vomiting, tinnitus, nystagmus, and giddiness. Additionally, it provides effective prophylaxis for motion sickness.

Note: Always use Cinarzin Plus under the guidance of a registered healthcare provider.

Pharmacology

Cinarzin Plus contains two active ingredients: Cinnarizine and Dimenhydrinate, which belong to distinct classes of medications. Cinnarizine is a calcium antagonist, which works by blocking calcium channels, helping to relax vascular smooth muscles, and improving blood flow. Dimenhydrinate is an antihistamine that reduces symptoms of nausea and vertigo (the sensation of dizziness or spinning). The combination of these two compounds offers enhanced therapeutic effects, making Cinarzin Plus more effective than either component when used individually.

Dosage & Administration

• Adults: Take one tablet three times a day after meals.
• Children and Adolescents under 18 years: Not recommended for use in this age group.
• Elderly: Dosage is the same as for adults.

Note: Always consult a registered healthcare provider before beginning treatment with Cinarzin Plus.

Interactions

The concurrent use of Cinnarizine and Dimenhydrinate with alcohol, CNS depressants, or tricyclic antidepressants may intensify their sedative effects. It is advised to avoid consuming alcohol or using these substances during treatment with Cinarzin Plus.

Contraindications

Cinarzin Plus should not be used in individuals who have:

• A known hypersensitivity to either of the active ingredients (Cinnarizine or Dimenhydrinate) or any of the excipients.
• Severe liver impairment.
• Angle-closure glaucoma, seizures, or raised intracranial pressure.
• A history of alcohol abuse or urinary retention due to urethroprostatic disorders.

Side Effects

Common side effects may include:

• Drowsiness
• Dry mouth
• Headache
• Stomach pain

Less common side effects may include:

• Impaired vision
• Allergic reactions (e.g., rash, itching)
• Sensitivity to light
• Difficulty urinating

Other potential effects include:

• Weight gain
• Constipation
• Chest tightness
• Jaundice
• Worsening of angle-closure glaucoma
• Uncontrolled movements
• Unusual excitement or restlessness
• Severe skin reactions

If any of these side effects persist or worsen, consult your healthcare provider immediately.

Pregnancy & Lactation

Cinarzin Plus is not recommended during pregnancy or breastfeeding. If its use is deemed necessary, it should only be administered under the guidance of a physician. Discontinuation of breastfeeding may be required during treatment.

Precautions & Warnings

• Hypotension: While Cinarzin Plus does not significantly affect blood pressure, caution should be exercised in patients with low blood pressure.
• Gastric Irritation: To minimize potential stomach upset, it is recommended to take Cinarzin Plus after meals.
• Parkinson’s Disease: Caution is advised when administering this medication to individuals with Parkinson’s disease.

Overdose Effects

Symptoms of overdose may include:

• Excessive drowsiness, dizziness, and lack of coordination
• Dry mouth, flushed skin, dilated pupils
• Increased heart rate (tachycardia), fever, headache
• Urinary retention

In case of an overdose, supportive treatment should be administered, and gastric lavage with an isotonic sodium chloride solution is recommended to remove the drug from the system.

Therapeutic Class:
Anti-vertigo drugs.

Storage Conditions:
Store in a cool, dry place (below 30°C), away from light and moisture. Keep out of reach of children.

Note: Always follow your healthcare provider’s guidance regarding dosage and usage.