Cinarzin Plus 20 mg+40 mg

Description

Indications

Cinarzin Plus is a medication designed to manage a variety of circulatory and balance disorders. It is effective in both the treatment and prevention of symptoms related to cerebral circulatory disturbances, such as:

• Cerebral Circulatory Disorders: This includes prophylactic and maintenance therapy for symptoms such as dizziness, tinnitus (ringing in the ears), vascular headaches, irritability, fatigue, early awakening, involutional depression, memory loss, poor concentration, and cognitive disturbances due to aging, including incontinence.

• Post-Cerebral and Cranial Trauma: Cinarzin Plus helps manage the sequelae resulting from cerebral or cranial trauma.

• Post-Apoplexy: This medication is used for the treatment of symptoms following a stroke (apoplexy).

• Migraine: It provides relief and prevention of migraine symptoms.

In addition, Cinarzin Plus offers significant benefits in managing peripheral circulatory disorders, including:

• Vascular spasms and arteriosclerosis (such as obliterating arteritis, thromboangitis obliterans, Raynaud’s disease).

• Conditions related to diabetes, including acrocyanosis, pernio, intermittent claudication, trophic and varicose ulcers, and paraesthesia.

• Treatment for nocturnal cramps, cold extremities, and pre-gangrene symptoms.

For balance disorders, this medication helps manage symptoms associated with labyrinthine arteriosclerosis and vestibular disorders, such as:

• Meniere’s Syndrome: This includes treatment for vertigo, dizziness, nausea, vomiting, tinnitus, and nystagmus.

• Motion Sickness: Cinarzin Plus is also used for the prevention of motion sickness.

Note: Always follow the guidance of a registered physician when using this medication.

Pharmacology

Cinarzin Plus contains two active ingredients: Cinnarizine and Dimenhydrinate, each belonging to different pharmacological classes:

• Cinnarizine is a calcium-channel blocker, which works by relaxing the smooth muscles of blood vessels, leading to vasodilation.

• Dimenhydrinate is an antihistamine that effectively reduces symptoms such as vertigo and nausea.

The combination of these two active ingredients in Cinarzin Plus provides enhanced therapeutic efficacy, offering more effective relief from dizziness, nausea, and other related symptoms compared to using either component alone.

Dosage & Administration

• Adults: Take 1 tablet three times daily, after meals.

• Children and Adolescents (under 18 years): This medication is not recommended for use in children or adolescents.

• Elderly: The dosage is the same as for adults.

Note: Always consult with a registered physician before starting this medication.

Interactions

• The concurrent use of alcohol, CNS depressants, or tricyclic antidepressants with Cinnarizine and Dimenhydrinate may increase the sedative effects of the drugs. It is recommended to avoid these substances while taking Cinarzin Plus.

Contraindications

Cinarzin Plus should not be used by individuals with:

• Known hypersensitivity to either of the active ingredients or any excipients in the formulation.

• Severe liver impairment.

• Angle-closure glaucoma, convulsions, suspected raised intracranial pressure, alcohol abuse, or urinary retention related to urethroprostatic disorders.

Side Effects

Common side effects include:

• Drowsiness
• Dry mouth
• Headaches
• Stomach pain

Rare side effects may include:

• Impaired vision
• Allergic reactions
• Sensitivity to light
• Difficulty urinating

Other possible side effects include:

• Weight gain
• Constipation
• Chest tightness
• Jaundice
• Worsening of angle-closure glaucoma
• Uncontrolled movements, restlessness, or severe skin reactions

If any severe reactions occur, seek medical advice immediately.

Pregnancy & Lactation

Cinarzin Plus should not be used during pregnancy or breastfeeding. If the use of this medication is deemed necessary by your healthcare provider, breastfeeding should be discontinued.

Precautions & Warnings

• While Cinarzin Plus does not significantly lower blood pressure, caution should be exercised when using this medication in individuals with hypotension.

• To minimize gastric irritation, the drug should be taken after meals.

• Exercise caution when prescribing this medication to patients with Parkinson’s disease.

Overdose Effects

In case of overdose, symptoms may include:

• Drowsiness
• Dizziness
• Ataxia (lack of coordination)
• Dry mouth
• Flushed skin
• Dilated pupils
• Tachycardia (increased heart rate)
• Fever
• Headache
• Urinary retention

In the event of overdose, general supportive treatment should be administered, and gastric lavage with isotonic sodium chloride solution is recommended.

Therapeutic Class

• Anti-vertigo drugs

Storage Conditions

• Store in a cool, dry place (below 30°C), away from light and moisture.
• Keep out of reach of children.

Always follow the advice of a registered physician regarding dosage and usage.