Colicon 10 mg

Description

Indications
Colicon is used for the treatment of various conditions related to muscle spasms in the gastrointestinal (GIT) and urinary systems. It is indicated for:

• Functional bowel disorder/Irritable bowel syndrome (IBS)
• Urinary incontinence due to an unstable detrusor muscle
• Infantile colic
• Gastrointestinal (GIT) spasms
• Colicky abdominal pain
• Diverticulitis
• Abdominal colic

Use this medication only as directed by a registered physician.

Pharmacology
Dicycloverine hydrochloride, the active ingredient in Colicon, is an antispasmodic and anticholinergic (antimuscarinic) agent. Chemically, it is classified as [Bicyclohexyl-]1-carboxylic acid, 2-(diethylamino) ethyl ester, hydrochloride. This medication works by relieving smooth muscle spasms in the gastrointestinal tract.

Dicycloverine specifically targets muscarinic (cholinergic) receptors found on the involuntary muscles of the gut walls. By blocking these receptors, it prevents the body’s natural chemicals from triggering muscle contractions, leading to muscle relaxation and relief from colic and abdominal spasms.

The injectable form of dicycloverine is a sterile, pyrogen-free, aqueous solution intended for intramuscular administration only (not for intravenous use). Oral administration is preferred as soon as possible.

Dosage & Administration

For oral administration:

• Adults: 10 to 20 mg, three times a day.
• Children (above 6 months): 5 to 10 mg, three times a day.

For injectable administration:

• Adults: 80 mg per day, divided into four intramuscular doses. This form is for short-term use only (1–2 days), and oral therapy should begin as soon as possible.
• Children: The dosage must be determined by a physician.

Use this medication only as directed by a registered physician.

Side Effects
Possible side effects of dicycloverine include:

• Insomnia
• Pupil dilation (mydriasis)
• Blurred vision (cycloplegia)
• Increased eye pressure
• Urinary hesitancy
• Heart palpitations
• Shortness of breath (dyspnea)

Pregnancy & Lactation
Dicycloverine is classified as Pregnancy Category B. Animal studies have not shown teratogenic or embryocidal effects. However, it should only be used during pregnancy if clearly necessary. There is limited data on whether dicycloverine is excreted in breast milk, so caution should be exercised when administering it to lactating mothers.

Precautions & Warnings
Dicycloverine should be used with caution in patients with the following conditions:

• Autonomic neuropathy
• Liver or kidney disease
• Ulcerative colitis
• Coronary heart disease
• Congestive heart failure
• Cardiac arrhythmias (tachyarrhythmia)
• Hiatal hernia
• Known or suspected prostate enlargement (prostatic hypertrophy)

Overdose Effects
Toxic reactions from dicycloverine overdose are rare. However, symptoms of overdose may include:

• Headache
• Nausea and vomiting
• Blurred vision
• Dilated pupils
• Dry, flushed skin
• Dizziness
• Dry mouth
• Difficulty swallowing
• Central nervous system (CNS) stimulation

Therapeutic Class
Anticholinergics (antimuscarinics) / Antispasmodics

Storage Conditions
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.