COMPIRON 30 ML

Indications

Compiron syrup is indicated for:

• Treatment of iron deficiency anemia: Including latent iron deficiency, macrocytic anemia, nutritional anemia in infants, anemia due to excessive hemorrhage, and anemia associated with infections or malignant diseases.

• Pregnancy-related iron deficiency anemia: Prevention and treatment before, during, and after pregnancy, as well as during lactation.

• Prophylactic therapy: To meet the recommended daily dietary allowances (RDA) for iron.

Consult a registered physician before use.

Pharmacology

Compiron syrup contains Iron Polymaltose Complex, a polysaccharide-iron preparation used for treating iron deficiency anemia. It features:

• Non-ionic ferric iron: Bound to polymaltose for controlled absorption upon contact with mucosal surfaces.

• No release of free radicals: Minimizing toxic effects often associated with ionized iron salts.

• Enhanced bioavailability: Unlike ferrous salts, it does not interact with food or medications, ensuring effective iron absorption for hemoglobin and myoglobin synthesis.

This advanced formulation ensures faster iron utilization while reducing common side effects of traditional iron preparations.

Dosage & Administration

Dosage and duration depend on the severity of iron deficiency and must be prescribed by a physician.

• Adults: 10 ml once or twice daily.

• Children (6–12 years): 10 ml daily.

• Children (2–6 years): 5 ml daily.

• Premature infants & infants: 3.33 mg of elemental iron per kg body weight.

Always follow the advice of a registered physician.

Interactions

• No significant interactions are typically observed due to the complex-bound nature of iron.

• Unlike ionic iron salts, Compiron does not interact with food components (e.g., phytates, oxalates, tannins) or other medications (e.g., tetracycline, antacids).

Contraindications

Compiron syrup should not be used in the following conditions:

• Risk of iron overload (e.g., hemochromatosis, thalassemia, or hemosiderosis).

• Known hypersensitivity to iron or any other ingredients in the syrup.

Side Effects

Compiron syrup is generally well-tolerated. However, mild side effects, including nausea, vomiting, constipation, or diarrhea, may occur.

Pregnancy & Lactation

• Pregnancy: Use during the first trimester only when the potential benefits outweigh risks. For the remainder of pregnancy, iron therapy may be prescribed under medical supervision.

• Lactation: Iron passes into breast milk in negligible amounts and is unlikely to cause adverse effects in infants.

Precautions & Warnings

• Overdosage can cause epigastric pain, diarrhea, and vomiting, potentially leading to metabolic acidosis, convulsions, or coma. In such cases:

  1. Administer an emetic.

  2. Perform gastric lavage with 1% sodium bicarbonate.

  3. Administer oral desferrioxamine to bind residual iron.

• Iron therapy should be used cautiously in patients with pre-existing gastrointestinal issues or conditions leading to iron overload.

Overdose Effects

In case of overdose:

• Immediate symptoms include epigastric pain, diarrhea, and vomiting.

• Serious complications may follow, such as metabolic acidosis, convulsions, or coma.

• Seek emergency medical attention and implement supportive treatments (e.g., gastric lavage, iron chelation).

Therapeutic Class

Oral Iron Preparations.

Storage Conditions

• Store below 30°C, away from light and moisture.

• Keep out of reach of children.