Cyclopan 10 mg

Description

Indications

Cyclopan is used for the treatment of:

• Functional bowel disorders, including irritable bowel syndrome (IBS)
• Urinary incontinence caused by an overactive detrusor muscle
• Infantile colic
• Gastrointestinal (GIT) spasms
• Colicky abdominal pain
• Diverticulitis
• Abdominal colic

Use this medication only as prescribed by a registered physician.

Pharmacology

Cyclopan contains dicycloverine hydrochloride, an antispasmodic and anticholinergic (antimuscarinic) agent. Chemically, it is classified as [Bicyclohexyl-]1-carboxylic acid, 2-(diethylammo) ethyl ester, hydrochloride. This medication works by relaxing the smooth muscles of the gastrointestinal tract, thereby alleviating spasms and associated pain.

Dicycloverine hydrochloride injection is a sterile, pyrogen-free, aqueous solution intended for intramuscular administration (not for intravenous use). It acts on cholinergic (muscarinic) receptors located in the gut wall, preventing certain chemicals from binding to these receptors. This inhibition results in muscle relaxation, reducing colic pain caused by gut contractions and spasms.

Dosage & Administration

For Oral Use

• Adults: 10 to 20 mg three times a day
• Children (above 6 months): 5 to 10 mg three times a day

For Injectable Use

• Adults: Administered via intramuscular injection only (not for intravenous use). The recommended dose is 80 mg per day, divided into four equal doses.
• Children: The dosage should be determined by a physician.

Oral administration should be initiated as soon as possible, and intramuscular injections should not be used for more than one to two days.

Use this medication only as prescribed by a registered physician.

Side Effects

Common side effects may include:

• Insomnia
• Pupil dilation (mydriasis) and difficulty focusing (cycloplegia)
• Increased ocular pressure
• Urinary hesitancy
• Palpitations
• Shortness of breath (dyspnea)

Pregnancy & Lactation

• Pregnancy Category B: Animal studies have shown no teratogenic or embryocidal effects. However, this medication should only be used during pregnancy if clearly necessary.
• There is no conclusive data on whether dicycloverine is excreted in breast milk. Therefore, caution should be exercised when prescribing to breastfeeding mothers.

Precautions & Warnings

Use with caution in patients with:

• Autonomic neuropathy
• Liver or kidney disorders
• Ulcerative colitis
• Coronary artery disease
• Congestive heart failure
• Cardiac tachyarrhythmia
• Hiatal hernia
• Known or suspected prostate enlargement (prostatic hypertrophy)

Overdose Effects

Overdose is rare but may cause the following symptoms:

• Headache
• Nausea and vomiting
• Blurred vision and pupil dilation
• Dry, hot skin
• Dizziness
• Dry mouth
• Difficulty swallowing
• Central nervous system (CNS) stimulation

Therapeutic Class

Anticholinergic (antimuscarinic) / Antispasmodic agents

Storage Conditions

• Store below 30°C, away from light and moisture.
• Keep out of reach of children.