CYCLOPAN 10 mg/5 ml

Description

Indications

Cyclopan is used for the management of:

• Functional bowel disorders, including irritable bowel syndrome (IBS)

• Urinary incontinence caused by an unstable detrusor muscle

• Infantile colic

• Gastrointestinal tract (GIT) spasm

• Colicky abdominal pain

• Diverticulitis

• Abdominal colic

Take this medication only under the guidance of a registered physician.

Pharmacology

Cyclopan contains dicycloverine hydrochloride, an antispasmodic and anticholinergic (antimuscarinic) agent. Chemically identified as [Bicyclohexyl-]1-carboxylic acid, 2-(diethylammo) ethyl ester, hydrochloride, it alleviates smooth muscle spasms of the gastrointestinal tract.

Dicycloverine HCl injection is a sterile, pyrogen-free aqueous solution intended for intramuscular use only (not for intravenous administration). It acts on cholinergic (muscarinic) receptors found in the involuntary muscles of the gut. By binding to these receptors, it blocks specific chemicals from interacting with them, leading to relaxation of the gut muscles. This mechanism reduces pain caused by colic and spasms of the gastrointestinal tract.

Dosage & Administration

For oral dosage forms:

• Adults: 10 to 20 mg three times a day.

• Children over 6 months of age: 5 to 10 mg three times a day.

For injectable dosage form:

• Adults: Intramuscular injection only. The recommended dose is 80 mg per day, divided into four equal doses.

• Oral administration of dicycloverine should begin as soon as possible. The intramuscular form is not recommended for use beyond 1-2 days.

• Children: Dosage must be determined by a physician.

Take this medication only under the guidance of a registered physician.

Side Effects

Common side effects may include:

• Insomnia

• Mydriasis (dilation of the pupils)

• Cycloplegia (paralysis of the eye’s ciliary muscle)

• Increased ocular tension

• Urinary hesitancy

• Palpitations

• Dyspnea (difficulty breathing)

Pregnancy & Lactation

• Pregnancy: Classified under Category B. Animal studies did not show teratogenic or embryocidal effects. Use during pregnancy only if clearly necessary.

• Lactation: There is no confirmed data on the secretion of this drug into breast milk. Use with caution in lactating mothers.

Precautions & Warnings

Use with caution in individuals with:

• Autonomic neuropathy

• Hepatic or renal impairment

• Ulcerative colitis

• Coronary heart disease

• Congestive heart failure

• Cardiac tachyarrhythmia

• Hiatal hernia

• Suspected or confirmed prostatic hypertrophy

Overdose Effects

Overdose symptoms are rare but may include:

• Headache

• Nausea

• Vomiting

• Blurred vision

• Dilated pupils

• Hot, dry skin

• Dizziness

• Dry mouth

• Difficulty swallowing

• CNS stimulation

Therapeutic Class

Anticholinergics (antimuscarinics)/Anti-spasmodics

Storage Conditions

Store below 30°C, away from light and moisture. Keep out of the reach of children.