Deslor 5 mg

Description

Indications
Deslor is primarily used for the relief of symptoms associated with both seasonal and perennial allergic rhinitis. These symptoms include sneezing, nasal discharge, itching, congestion or stuffiness, ocular itching, tearing, redness, and itching of the palate. Additionally, Deslor is effective in managing chronic idiopathic urticaria, alleviating symptoms such as itching, as well as reducing the size and number of hives.

Use as directed by a registered medical practitioner.

Pharmacology
Desloratadine, the active metabolite of Loratadine, is a long-acting, non-sedating antihistamine. It selectively antagonizes H1 histamine receptors, offering effective histamine blockade. In addition, Desloratadine has the ability to inhibit histamine release from human mast cells, contributing to its therapeutic effects.

Dosage & Administration
Pediatric Drops

• Children aged 6-11 months: 2 ml once daily
• Children aged 1-2 years: 2.5 ml once daily

Syrup

• Children aged 6-11 months: 2 ml once daily
• Children aged 1-5 years: 2.5 ml once daily
• Children aged 6-11 years: 5 ml once daily
• Adults and children over 12 years of age: 10 ml once daily

Tablet

• Adults and children aged 12 years and over: 1 tablet daily

Use as directed by a registered medical practitioner.

Interaction
No clinically significant drug interactions have been reported with Desloratadine.

Contraindications
Desloratadine is contraindicated in patients with hypersensitivity to Desloratadine, any of its components, or Loratadine.

Side Effects
While generally well-tolerated, some individuals may experience less common side effects, including headache, nausea, fatigue, dizziness, sore throat, indigestion (dyspepsia), and muscle pain (myalgia).

Pregnancy & Lactation
Pregnancy Category C. The safety of Desloratadine during pregnancy has not been fully established. It should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus. Desloratadine passes into breast milk, and therefore, a decision should be made whether to discontinue breastfeeding or to stop taking Desloratadine, considering the importance of the drug to the mother.

Precautions & Warnings
In patients with liver or renal impairment, a reduced starting dose is recommended. For adults with liver or renal issues, it is advised to begin with one 5 mg tablet every other day, as per pharmacokinetic data. Desloratadine should also be used with caution in patients with a history of seizures, whether medical or familial.

Use in Special Populations
Desloratadine is recommended for use in children and adolescents under the guidance of a healthcare provider.

Overdose Effects
No clinically significant adverse effects have been reported with overdose.

Therapeutic Class
Deslor belongs to the class of non-sedating antihistamines.

Storage Conditions
Store in a cool, dry place, away from direct light. Keep the medicine below 30°C and out of reach of children.