Diapro MR 30 mg

Description

Indications
Diapro MR is an oral antidiabetic medication belonging to the sulfonylurea class, used to help lower blood sugar levels in people with type 2 diabetes mellitus. It is typically prescribed when diet, exercise, and weight management alone are insufficient to control blood sugar levels.

Take the medicine as prescribed by a registered healthcare provider.

Pharmacology
The active ingredient, Gliclazide, is a second-generation sulfonylurea that works by stimulating insulin release from the pancreatic β-cells. It enhances calcium transport across the β-cell membranes and reduces glucose production in the liver, helping to lower blood sugar levels.

Dosage & Administration

• Film-coated tablets: The usual starting dose is between 40 mg to 80 mg daily. Depending on your blood sugar levels, this dose can be increased up to 320 mg daily in divided doses. The medicine should be taken before meals.
• Modified-release preparation: Always follow your doctor’s or pharmacist’s instructions regarding the dosage. Your doctor will adjust the dose based on your blood sugar and other factors. The typical dose is between one and four tablets (maximum 120 mg) once daily with breakfast. Take the tablets with a glass of water and swallow them whole; do not chew or crush the tablets. It is essential to have a meal after taking the tablets.

If Diapro MR is prescribed in combination with other medications such as metformin, an alpha-glucosidase inhibitor, or insulin, your doctor will adjust the doses of each medication based on your specific needs.

• Overdose: If you take too many tablets, seek immediate medical assistance. Overdose symptoms may include signs of low blood sugar (hypoglycemia). Consume sugar or sugary drinks to alleviate symptoms, followed by a substantial meal. If the person is unconscious, do not administer food or drink, and call for emergency medical assistance.
• Missed dose: If you forget to take a dose, take it as soon as you remember, unless it’s almost time for your next dose. Do not double the dose to make up for a missed one.
• Stopping treatment: Discontinuing Diapro MR may lead to high blood sugar (hyperglycemia). Always consult your doctor before stopping this medication.

Take the medicine as prescribed by a registered healthcare provider.

Interactions
Tell your doctor or pharmacist if you are taking or have recently taken any other medications. Diapro MR can interact with several drugs, potentially affecting blood sugar levels. Some medicines may increase the risk of hypoglycemia (low blood sugar), such as other antidiabetic drugs, antibiotics (e.g., sulphonamides), and certain heart and blood pressure medications. On the other hand, some medications like corticosteroids or diuretics may weaken its blood sugar-lowering effect.

Contraindications
Diapro MR should not be used if:

• You are allergic to gliclazide or other sulfonylureas.
• You have insulin-dependent diabetes (type 1).
• You have diabetic ketoacidosis, diabetic pre-coma, or coma.
• You suffer from severe kidney or liver disease.
• You are breastfeeding.

Side Effects
Like all medications, Diapro MR can cause side effects, although not everyone experiences them. Common side effects include:

• Hypoglycemia (low blood sugar): Symptoms may include hunger, dizziness, confusion, sweating, or in severe cases, loss of consciousness.
• Liver disorders: Signs of liver dysfunction, such as yellowing of the skin and eyes, may occur. Consult your doctor if these symptoms appear.
• Skin reactions: Rash, itching, or swelling may occur. Severe allergic reactions, such as difficulty breathing, should be treated immediately.
• Blood disorders: Decrease in blood cell counts can result in symptoms like bruising, sore throat, or fever.
• Digestive issues: Abdominal pain, nausea, or diarrhea may occur.

Pregnancy & Lactation
Diapro MR is not recommended during pregnancy. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medication.

Precautions & Warnings
Before using Diapro MR, discuss your medical history and current medications with your doctor. Regular monitoring of blood sugar levels is necessary, especially during the early stages of treatment. Take extra care to avoid hypoglycemia (low blood sugar), which can occur in cases such as skipping meals, fasting, or excessive physical activity. If you experience symptoms of low blood sugar, consume sugar immediately.

In stressful situations (e.g., surgery, illness), your doctor may switch you to insulin temporarily.

Therapeutic Class
Sulfonylureas

Storage Conditions
Store Diapro MR below 30°C, away from light and moisture. Keep it out of the reach of children. Do not use the medication past the expiry date printed on the packaging.

Chemical Structure

• Molecular formula: C15H21N3O3S
• Chemical structure: Gliclazide’s chemical structure

Common Questions about Diapro MR 30 mg Tablet

1. What is Diapro MR 30 mg MR Tablet?
   Diapro MR 30 mg is an oral medication for managing type 2 diabetes. It helps regulate blood sugar levels by promoting insulin release and improving the body’s response to existing insulin.
2. What happens if I take Diapro MR 30 mg MR Tablet without eating?
   Diapro MR should be taken with food to help regulate blood sugar. If you miss a meal, skip the dose.
3. What if I missed a dose?
   If you forget a dose, take it as soon as possible unless it’s close to your next scheduled dose. Do not take two doses together.
4. How long does the effect last?
   The effects of Diapro MR last for approximately 24 hours.
5. Can I use Diapro MR during pregnancy?
   Diapro MR is not recommended for use during pregnancy.

General Instructions
Take Diapro MR exactly as prescribed by your healthcare provider. Monitor your blood sugar levels regularly, and always keep sugar or glucose tablets with you to manage any potential hypoglycemia.