Duralax 5 mg

Description

Indications
Duralax is prescribed for:

• Relief from constipation.
• Bowel preparation before radiographic or endoscopic examinations.

Use this medication only as directed by a registered physician.

Pharmacology
Bisacodyl, the active ingredient in Duralax, is a diphenolic compound structurally similar to phenolphthalein. It is commonly used as a stimulant laxative. Bisacodyl acts on the colon to enhance peristalsis and increases water and electrolyte content in the intestinal lumen, promoting bowel movement. When applied to the caecum, it triggers a response throughout the colon.

Dosage & Administration

For Constipation:

• Adults: 5-10 mg at bedtime; in some cases, the dose may be increased to 15-20 mg if necessary.
• Children under 10 years: 5 mg.

For Bowel Preparation Before Radiological Procedures or Surgery:

• Adults: 10 mg orally at bedtime for two consecutive days before the examination.
• Children: Half of the adult dose.

Use this medication only as directed by a registered physician.

Contraindications
Duralax should not be used in individuals with:

• Ileus or intestinal obstruction
• Acute surgical abdominal conditions such as acute appendicitis
• Acute inflammatory bowel diseases
• Severe dehydration

Side Effects
When taken at the recommended dosage, Duralax is generally well-tolerated. However, excessive use may lead to diarrhea, malabsorption, and potassium depletion.

Pregnancy & Lactation
Like other medications, Bisacodyl should be avoided during pregnancy, particularly in the first trimester. For breastfeeding mothers, it should be used with caution.

Precautions & Warnings

• Overuse of Duralax can lead to fluid and electrolyte imbalances.
• Prolonged use may result in dependence on laxatives for bowel movements.

Therapeutic Class
Stimulant laxatives

Storage Conditions
Store in a cool, dry place, away from direct light.