Zemicef 200 mg

Indications:
Zemicef is used for treating bacterial infections, including:

• Upper Respiratory Tract Infections (URTI) such as otitis media and bronchitis.
• Urinary Tract Infections (UTIs) like cystitis and pyelonephritis.
• Conditions caused by common pathogens, including Streptococcus pneumoniae, E. coli, and Klebsiella species.

Pharmacology:
Cefixime, the active ingredient, is a third-generation cephalosporin. It works by inhibiting bacterial cell wall synthesis and is stable against beta-lactamase enzymes. Absorption is around 40-50% and unaffected by food.

Dosage & Administration:

• Adults & Children (10+ years or >50 kg): 200-400 mg/day, taken as a single or divided dose.
• Children (1-10 years): 8 mg/kg/day (doses vary by age).
• Typhoid in children: 5 mg/kg twice daily for 10-14 days.
• Renal impairment: Dose adjustments required if creatinine clearance <20 ml/min.

Contraindications:

• Known hypersensitivity to cephalosporins.

Side Effects:

• Common: Diarrhea, abdominal pain, nausea, vomiting, headache, dizziness.
• Rare: Pseudomembranous colitis, hypersensitivity reactions, and transient changes in liver/renal function tests.

Precautions:

• Use cautiously in penicillin-sensitive patients due to potential cross-allergy.
• Monitor for antibiotic-associated diarrhea.
• Avoid use in pregnancy and lactation unless essential.

Pregnancy & Lactation:
There are no adequate human studies, so use only if necessary. It’s unclear if Cefixime is excreted in breast milk.

Storage:
Store below 30ºC, protected from light and moisture. Keep out of children’s reach.

Quick Tips:

• Complete the full course to prevent antibiotic resistance.
• Take with food to minimize stomach upset.
• Inform your doctor if you experience severe diarrhea or allergic reactions.
• Avoid alcohol during treatment.

Note: Always use Zemicef 200 mg Capsule under a registered physician’s advice.