Ace Plus 500 mg+65 mg

Description

Introduction:
Ace Plus combines the proven pain-relieving power of Paracetamol with the added benefits of Caffeine to deliver fast and effective relief from various types of pain and discomfort. Ideal for treating headaches, migraines, toothaches, neuralgia, and fever, Ace Plus is a go-to solution for managing common symptoms of illness and injury. It also offers additional benefits in reducing body temperature and treating aches and pains associated with colds and flu.

Indications:
Ace Plus is indicated for the following conditions:

• Headache
• Migraine
• Toothache
• Neuralgia (nerve pain)
• Feverishness
• Period Pain
• Sore Throat
• Backache
• Aches and Pains from Colds and Flu
• Help to Reduce Body Temperature

Consult a registered healthcare professional before use.

Pharmacology:
Ace Plus combines Paracetamol and Caffeine to enhance the effectiveness of pain relief:

• Paracetamol is a widely recognized analgesic (pain reliever) and antipyretic (fever reducer), with mild anti-inflammatory properties. It works by inhibiting the production of prostaglandins in the brain, reducing pain and fever.
• Caffeine, an alkaloid and xanthine derivative, complements Paracetamol by increasing its solubility and absorption. Caffeine raises the pain threshold and enhances pain tolerance. Additionally, it acts on the brain’s blood vessels, providing relief for headaches and migraines by improving vascular tone and reducing blood flow constriction.

This combination works synergistically to provide faster, more effective pain relief and fever control.

Dosage & Administration:

• Adult Dose: Take 1-2 tablets every 4-6 hours. Do not exceed 8 tablets per day.
• Child Dose: Not recommended for children under 12 years of age.
  Always follow your healthcare provider’s recommendations before use.

Interaction:
Ace Plus may interact with the following medications:

• Anticonvulsants (e.g., phenytoin, barbiturates, carbamazepine): May reduce serum levels of Paracetamol.
• Anticoagulants (e.g., warfarin): May enhance anticoagulant effects with prolonged use.
• Metoclopramide & Domperidone: Accelerates the absorption of Paracetamol.
• Probenecid: May increase Paracetamol serum levels.
• Chloramphenicol: May increase serum levels of Paracetamol.
• Colestyramine: May reduce absorption of Paracetamol within 1 hour of administration.
• Phenothiazine: May cause severe hypothermia.

Always inform your doctor about any other medications you’re taking.

Contraindications:
Ace Plus is contraindicated in the following conditions:

• Severe renal impairment or hepatic disease (e.g., Viral Hepatitis).
• Known hypersensitivity to Paracetamol or Caffeine.
• Do not use in patients with a history of liver disease or kidney problems without medical supervision.

Side Effects:
Side effects of Paracetamol are typically mild but may include:

• Hematological reactions such as thrombocytopenia, leukopenia, pancytopenia, neutropenia, and agranulocytosis.
• Pancreatitis, skin rashes, and other allergic reactions may occasionally occur.

Consult your doctor if you experience severe side effects.

Pregnancy & Lactation:

• Pregnant women should consult with their healthcare provider before taking Ace Plus.
• Ace Plus can be taken while breastfeeding, but always follow your doctor’s guidance.

Precautions & Warnings:

• Use with caution in individuals with hepatic (liver) or renal (kidney) impairment.
• Avoid prolonged use without medical advice, especially in patients taking other hepatotoxic medications.
• Always adhere to the recommended dosage to avoid potential liver damage.

Overdose Effects:
In case of overdose, symptoms in the first 24 hours may include:

• Pallor, nausea, vomiting, anorexia, and abdominal pain.
• Liver damage may become apparent 12 to 40 hours after ingestion.
• Potential glucose metabolism abnormalities and metabolic acidosis.

Seek immediate medical attention if overdose is suspected.

Therapeutic Class:
Non-opioid analgesics – Pain relief and fever management.

Storage Conditions:
Store Ace Plus in a cool, dry place. Protect from light and moisture. Keep out of the reach of children.