Asynta

Description

Here is the rewritten product description for Asynta, maintaining accuracy and clarity, while ensuring it is well-structured:

Indications
Asynta is used to treat symptoms associated with the reflux of acid, bile, and pepsin into the esophagus. These symptoms include acid regurgitation, heartburn, and indigestion. It is commonly prescribed following gastric surgery, for conditions like hiatus hernia, during pregnancy, or in cases of reflux esophagitis. Asynta is also effective in addressing symptoms related to laryngopharyngeal reflux, such as hoarseness, voice disorders, sore throats, and cough. Additionally, it can alleviate symptoms of gastroesophageal reflux disease (GERD) during or after discontinuation of acid-suppressing therapies.
Note: Always follow the advice of a registered healthcare professional before taking this medication.

Pharmacology
Asynta is a combination of two active ingredients: Sodium Alginate and Potassium Bicarbonate.

• Sodium Alginate is a naturally occurring substance that, when it reacts with stomach acid, forms a gel.
• Potassium Bicarbonate also reacts with stomach acid to produce carbon dioxide bubbles.

These bubbles become trapped within the gel formed by Sodium Alginate, allowing it to float on top of the stomach contents like a raft. This raft effectively prevents acid from flowing back into the esophagus, providing relief from heartburn and other reflux symptoms. This mechanism is purely physical, meaning it does not rely on systemic absorption. The raft can remain in place for up to four hours before being broken down and eliminated in the digestive system.

Dosage and Administration

Tablet Form:

• Adults and children over 12 years: 1-2 tablets, 3-4 times a day, after meals and before bedtime.
• Children 6-12 years: ½-1 tablet, 3-4 times a day, after meals and before bedtime.

Suspension Form:

• Adults and children 12 years and older: 5-10 mL (1-2 teaspoonfuls), 3-4 times a day, after meals and before bedtime.
• Children 2-12 years: 2.5-5 mL (½-1 teaspoonful), 3-4 times a day, after meals and before bedtime.

Use in Children:

• Not recommended for children under 2 years of age.

Elderly and Hepatic Impairment:

• No dosage modifications are necessary.

Renal Insufficiency:

• Caution is advised if a highly restricted salt diet is necessary.

Note: Always follow the advice of a registered healthcare professional before taking this medication.

Interactions
A two-hour interval should be observed between taking Asynta and the administration of other medications, especially tetracyclines, fluoroquinolones, iron salts, thyroid hormones, chloroquine, bisphosphonates, and estramustine.

Contraindications
Asynta should not be used by individuals with known hypersensitivity to Sodium Alginate or Potassium Bicarbonate.

Side Effects
While side effects are rare, they may include nausea, constipation, diarrhea, or headaches. In cases of excessive dosage, a sensation of swelling may occur. If any side effects are experienced, or in the event of an overdose, please consult a healthcare professional.

Pregnancy and Lactation
Asynta can be used during pregnancy if clinically necessary. No known harmful effects have been observed in breastfed infants, and the medication is considered safe for use while breastfeeding.

Precautions and Warnings
Asynta should be prescribed with caution for patients with renal impairment or congestive heart failure. It should also be used carefully in those with hypercalcemia, nephrocalcinosis, or a history of calcium-containing kidney stones. The effectiveness of the treatment may be reduced in individuals with very low levels of gastric acid. If symptoms do not improve within seven days, a clinical evaluation is recommended.

Overdose Effects
Overdose of Asynta is rare. In the event of an overdose, immediate consultation with a healthcare professional is advised.

Therapeutic Class
Antacids

Storage Conditions
Store in a cool, dry place below 30°C, away from light and moisture. Keep out of reach of children.

Note: Always follow the advice of a registered healthcare professional before taking this medication.